Extended amygdala and uncertainty

Relative to the centromedial amygdala (CM), the bed nucleus of the stria terminalis (BNST) may exhibit more sustained activation toward threat, sensitivity to unpredictability, and activation during anxious anticipation. These factors are often intertwined. For example, greater BNST (vs. CM) activation during a block of aversive stimuli may reflect either more sustained activation to the […]

High-resolution connectivity of the extended amygdala

The extended amygdala has been implicated as a critical region in the neurocircuitry underlying anxiety. The circuitry of the extended amygdala, including the central (CeA) and basolateral (BLA) nuclei of the amygdala and the bed nucleus of the stria terminalis (BNST), has been well-defined in non-human animals; however, much less is known about the roles […]